If acute tubular necrosis is the diagnosis, and the cause is remedied, then recovery will probably occur fairly quickly. Under normal conditions these cells continually replace themselves, but with tubular necrosis, 99 percent of the water is absorbed, causing the salt and metabolic byproducts in the urine to be concentrated. This is a condition that involves the dying of cells that form the tube that transports urine. One of the conditions that will need to be ruled out or confirmed as a source of the cylindruria is acute tubular necrosis. In order to reach a diagnosis, your veterinarian will want to know whether your cat has been exposed to any of the toxins or drugs mentioned above.Ī closer analysis of the casts in the urine will give your veterinarian some clues as to what is causing this irregularity. A condition resulting from proteins, called amyloids, that have been altered to take on an insoluble form and have deposited themselves into organs and/or tissues.Glomerulonephritis describes the inflammation of the small blood vessels in one or more of the glomeruluses, it is presented by hypertension, swelling (edema), and blood protein deposits.The glomerulus serves as a filtering unit in the kidneys, removing waste matter from the blood): Glomerular Disease (Arteries branch inside the kidneys into clusters of blood vessels, each of which is called a glomerulus. Infectious diseases, such as Rocky Mountain spotted fever, can cause the kidney to become inflamed and drop particles into the urine.When the kidney is inflamed – swollen and irritated – the kidneys drop protein and red blood cells into the urine.Myoglobulinuria - migration of globulin (blood plasma protein), to the kidneys, excreted in the urine.Hemoglobinuria - protein hemoglobin, the oxygen carrying pigment that makes the blood red, drops into the urine and is also found in high concentrations in the kidney.Renal vessel thrombosis (coagulation, or clotting, of blood in the vessels that feed the kidney and surrounding area).Low cardiac output (e.g., congestive heart failure, cardiac arrhythmia, or pericardial disease ).Renal Ischemia (conditions under which the normal flow of blood to the kidneys is blocked or restricted): Intravenously administered radiocontrast agent, used in diagnostics.
Non-steroidal anti-inflammatory drugs (NSAIDs).Antifreeze, grape/raisin ingestion, excessive calcium in the blood.Nephrotoxicosis (toxins, both chemical and medicinal, that affect the kidneys): Listed below are several possible conditions that would affect the body or its organs in such a way that it responds by dropping excess particles into the urine. If there is particle matter in your cat's urine, you will need to have a urinalysis done within two hours of excretion, since the casts will typically dissolve after two hours. The medical term for this condition is cylindruria, and it is characterized by an abnormally high amount of particle matter (casts) in the urine sediment. Particle matter in the urine may indicate that there is a primary kidney disease, or that there is a systemic disorder that is affecting the kidneys secondarily.
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